Table 4.

BOLD Percent Signal Change Contrast between Alcohol and Neutral Pictures for Baseline and Follow-up

Anatomical Region	Heavy Drinkers BOLD Value	Controls BOLD Value	t-test p-values	η2 of Group × Time Interaction
L ACC BL	1.56 (2.2)	−2.51 (4.2)	<.001	.09a
L ACC FU	1.33 (2.7)	−0.37 (2.7)	.07
R DSGP BL	0.00 (1.5)	−1.60 (1.5)	.002	ns
R DSGP FU	0.11 (1.4)	−0.47 (1.3)	.21
L DS BL	0.02 (1.5)	−1.56 (1.5)	.003	ns
L DS FU	0.02 (1.2)	−0.72 (1.3)	.08
L Cerebellum BL	1.19 (2.1)	−1.88 (1.5)	<.001	ns
L Cerebellum FU	0.96 (2.7)	−0.20 (1.8)	.15
R Cerebellum BL	0.60 (1.8)	−1.77 (1.2)	<.001	.14*
R Cerebellum FU	−0.48 (2.6)	−0.84 (1.4)	.62
Parahip. BL	1.00 (1.9)	−1.50 (1.1)	<.001	ns
Parahip. FU	−0.02 (2.5)	−0.78 (2.2)	.33

Notes: R = right; L = left; BL = baseline; FU = follow-up. ACC = anterior cingulate cortex; DSGP = dorsal striatum and globus pallidus; Parahip. = Parahippocampal gyrus extending to thalamus/substantia nigra. Values are Mean(SD). Positive BOLD values indicate greater response to alcohol pictures vs. neutral beverage pictures; negative BOLD values indicate less response to alcohol pictures compared to neutral beverages.

^ap = .07;

^*p < .05