Table 2.
Chemotherapy regimens used after progression following second-line chemotherapy
| Platinum combination therapy | Docetaxel monotherapy | |||
|---|---|---|---|---|
| Third-line | ≥Fourth-line | Third-line | ≥Fourth-line | |
| EGFR-TKI | ||||
| Gefitinib | 1 | 1 | 11 | 5 |
| Erlotinib | 2 | 0 | 5 | 7 |
| Single agent | ||||
| Docetaxel | 0 | 1 | - | 1 |
| Pemetrexed | 2 | 0 | 2 | 3 |
| Amrubicin | 2 | 1 | 8 | 11 |
| Gemcitabine | 0 | 1 | 16 | 8 |
| S1 | 0 | 0 | 5 | 12 |
| Others | 2 | 0 | 1 | 5 |
| Platinum combination | 3 | 0 | 0 | 5 |
| Investigational agent | 0 | 0 | 1 | 4 |
Abbreviations: EGFR-TKI, epidermal growth factor receptor tyrosine kinase inhibitor.