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. 2015 Mar;31(1):77–88. doi: 10.5487/TR.2015.31.1.077

Table 2. Urinalysis data of Beagle dogs orally administered with Lithospermum erythrorhizon hexane extract for 4 weeks.

Week 0 (Pre) Week 4 of Dosing Week 2 of Recovery



Sex Male Female Male Female Male Female







Dose (mg/kg/day) 0 30 100 300 0 30 100 300 0 30 100 300 0 30 100 300 0 300 0 300

No. of animals 5 3 3 5 5 3 3 5 5 3 3 5 5 3 3 5 2 2 2 2
Color Pale yellow 1 3 2 4 2 3 2 2 2 1 1
Yellow 4 3 3 1 1 3 3 3 1 4 2 2 1 2 2 2 2
Amber 1 4 1 1
Brown 3
pH 5 2 1 1
6 1 2 1
6.5 1 1 1 1
7 1 1 1
8 3 2 1 3 2 3 3 3 5 3 3 4 4 1 3 2 1
9 1 1 2 3 2 1 1
Protein (mg/dL) - 3 3 2 5 4 3 3 5 3 2 2 2 5 2 3 1 1 1 2 2
25 2 1 1 2 1 1 3 1 4 1 1
Glucose (mg/dL) - 5 3 3 5 5 3 3 5 5 3 3 5 5 3 3 5 2 2 2 2
50
Ketone body (mg/dL) - 5 3 2 5 5 3 3 5 5 3 2 2 4 2 2 2 2 2 1 2
5 1 1 3 1 1 1 3 1
Bilirubin (mg/dL) - 5 3 2 5 5 3 3 5 5 3 1 5 5 2 3 3 2 2 2 2
1 1 1 1 2
3 1

Week 0 (Pre) Week 4 of Dosing Week 2 of Recovery



Sex Male Female Male Female Male Female







Dose (mg/kg/day) 0 30 100 300 0 30 100 300 0 30 100 300 0 30 100 300 0 300 0 300

Erythrocyte (Ery/μL) - 2 1 1 5 4 3 3 5 3 1 2 4 5 3 3 4 1 2 2 2
10 2 2 2 1 1 1
25 1 1 1 1 1
50 1
150 1
Cast 0 5 3 3 5 5 3 3 5 5 3 3 5 5 3 3 5 2 2 2 2
1~5
Epithelia cell 0 5 3 3 5 5 3 3 5 5 3 3 5 5 3 3 5 2 2 2 2
1~5

: Number of counts in 20 visual fields, 400×.