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. 2015 Feb 3;23(4):648–655. doi: 10.1038/mt.2015.2

Figure 2.

Figure 2

Functional characterizations of three different bispecific antibodies with FLT3 X CD3-specificity. Symbols (•, ▪, ▴) were assigned as indicated. In c–f, a Fabsc-antibody with CSPG4 X CD3 specificity (♦) was used as a negative control. In d–f, empty and filled symbols refer to the absence and presence, respectively of FLT3+ NALM-16 target cells. The binding experiment depicted in a and b was repeated once with almost identical results. In c–f, representative results from one out of three experiments with peripheral blood mononuclear cells from different healthy donors are shown.