Table 2.
Mammalian sympathetic neurotransmitters and their receptors
| Neurotransmitters | Receptors | Neuropeptide genes | Neurotransmitter receptor genes |
|---|---|---|---|
| Catecholaminergic | |||
| Norepinephrine or noradrenaline (NA) | ≤10−8 M: α 1a-, b-, d- adrenoceptors | ADRA1A, ADRA1B, ADRA1D | |
| ≤10−8 M: α 2a-, b-, c-adrenoceptors | ADRA2A, ADRA2B, ADRA2C | ||
| ≥10−6 M: β1-, β2-, β3-adrenoceptors | ADRB1, ADRB2, ADRB3 | ||
| Peptidergic | |||
| Vasoactive intestinal peptide (VIP) | VIP-1, VIP-2, and VIP/PACAP receptors | VIP | VIPR1, VIPR2 |
PACAP, pituitary adenylate cyclase-activating polypeptide.