Table 2.

Estimated absorbed doses (mGy/MBq) of [¹⁷⁷Lu]-DO3A-VS-Cys⁴⁰-Exendin-4 in human females and males extrapolated from rat organ distribution data

ORGAN	FEMALE	MALE
Kidneys	5.880	6.040
Adrenals	0.051	0.041
Liver	0.053	0.026
LLI wall*	0.071	0.049
ULI wall**	0.075	0.052
Red marrow	0.117	0.081
Spleen	0.058	0.036
Osteogenic cells	0.484	0.303
Small intestine	0.093	0.065
Ovaries/Testes	0.031	0.007
Urinary Bladder Wall	0.071	0.050
Breasts	0.068	NA
Uterus	0.071	NA
Stomach wall	0.076	0.053
Thymus	0.071	0.049
Thyroid	0.068	0.047
Gall bladder wall	0.078	0.056
Skin	0.066	0.045
Lungs	0.752	0.676
Heart wall	0.018	0.013
Muscle	0.013	0.009
Pancreas	0.067	0.051
Brain	0.069	0.047
Total body	0.119	0.088
Total effective dose (mSv/MBq)	0.295	0.265

^*LLI: lower large intestine;

^**ULI: upper large intestine.