BLI monitoring of 231/luc orthotopic breast tumor response to IP administration of saline, CA4P or OXi8007. A. Maximum BLI signal was observed around 15 minutes post SC injection of luciferin at baseline, 4, 24, 48 and 72 hours post injection of saline (control), CA4P and OXi8007 in representative mice. B-D. Corresponding dynamic time courses of total flux obtained at the five time points for these three mice (B. Saline; C. CA4P; D. OXi8007).