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. 2015 Jan 15;5(2):96–108.

Table 1.

18F-FCH PET/CT for local disease (detection of malignancy in prostate gland)

Article Authors Year No. of patients Findings
1 [28] Kwee et al. 2005 17 Prostate sextants positive for malignancy showed higher SUV-max than biopsy negative sextants
2 [30] Schmid et al. 2005 19 Only 1 out of 9 patients with 18F-FCH uptake proved to be malignant
3 [17] Husarik et al. 2008 43 Pathologic uptake was noted in 42 out of 43 patients with histologic proven PCa
4 [18] Igerc et al. 2008 20 Five out of 13 positive focal 18F-FCH uptake were malignant on pathology
5 [29] Kwee et al. 2008 15 Sixty one out of 90 prostate sextants with 18F-FCH uptake were malignant on pathology
6 [15] Beheshti et al. 2010 130 Good correlation between sections with the highest 18F-FCH uptake and malignancy

Abbreviations: PCa, prostate cancer; 18F-FCH. [18F]fluoromethyl-dimethyl-2-hydroxyethyl-ammonium; SUV, standardized uptake value.