Table 1.

Expression of CRT in different cancers.

Cancer	CRT levels*	Clinical outcomes	Reference
Oral	Increased	—	[43]
Esophagus	Increased	↓ survival (poor prognosis)	[44]
Breast	Increased	↑ metastasis, ↑ invasion, ↓ survival	[45–47]
Pancreas	Increased	↑ lymph node metastasis, ↑ UICC stage, ↓ survival	[48]
Gastric	Increased	↑ lymph node metastasis, ↑ invasion, ↑ microvessel density, ↓ survival	[49]
Colon	Increased	—	[50]
Bladder	Increased	↑ urinary CRT, ↑ histological grade, ↑ pathological T stage	[51–53]
Prostate	Increased	—	[54]
Vagina	Increased	—	[55]
#Ovarian	Increased	Better response to chemotherapy	[55, 56]
#Neuroblastoma	Increased	↑ differentiation, ↑ survival	[57]

↑: increased; ↓: decreased.

^*CRT levels in tumor tissue except ovarian carcinoma in effusion fluids.

^#Higher levels of CRT seem to correlate with good prognosis for the diseases.