Table 4.

Clinical and pathologic characteristics of 92 epithelial ovarian cancer patients and their association to Lewis y, CD44, CD147, HE4, integrin α5, β1, αv, β3 protein expression

Variable	N	Lewis y			CD44			CD147			HE4			Integrin α5			Integrin β1			Integrin αv			Integrin β3
		L	H	P	L	H	P	L	H	P	L	H	P	L	H	P	L	H	P	L	H	P	L	H	P
		45	47		48	44		46	46		48	44		48	44		44	48		46	46		45	47
Age at diagnosis				0.672			0.464			1.000			0.058			0.837			0.397			0.293			0.918
≤ 60	74	37	37		40	34		37	37		35	39		39	35		37	37		39	35		36	38
> 60	18	8	10		8	10		9	9		13	5		9	9		7	11		7	11		9	9
FIGO Stage				0.090			0.212			0.825			0.420			0.420			0.715			0.123			0.418
I-II	31	19	12		19	12		16	15		18	13		18	13		14	17		19	12		17	14
III-IV	61	26	35		29	32		30	31		30	31		30	31		30	31		27	34		28	33
Differentiation				0.770			0.322			0.974			0.839			0.487			0.754			0.281			0.214
Well	14	8	6		9	5		7	7		8	6		8	5		7	7		5	9		5	9
Moderate	43	21	22		24	19		22	21		23	20		23	20		22	21		25	18		19	24
Poor	35	16	19		15	35		17	18		17	18		16	19		15	20		16	19		21	14
Pathological Subtype				0.555			0.894			0.662			0.313			0.760			0.148			0.662			0.304
Serous carcinoma	60	28	32		31	29		31	29		29	31		32	28		32	28		29	31		27	33
Non-serous carcinoma	32	17	15		17	15		15	17		19	13		16	16		12	20		17	15		18	14
Lymph node metastasis				0.060			0.160			0.116			0.160			0.953			0.082			0.822			0.595
No	63	35	28		36	27		35	28		36	27		33	30		34	29		32	31		32	31
Yes	29	10	19		12	17		11	18		12	17		15	14		10	19		14	15		13	16
Residual tumor size				0.010*			0.024*			0.291			0.157			0.066			0.569			0.058			0.381
≤ 1 cm	53	32	21		33	20		29	24		31	22		32	21		24	29		31	22		28	25
> 1 cm	39	13	26		15	24		17	22		17	22		16	23		20	19		15	24		17	22

^*P< 0.05.

Abbreviation: HE4, Human epididymis protein 4; L, low expression; H, high expression. The bold entries place emphasis on statistically significant P-values.