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. 2015 Mar;10(3):451–456. doi: 10.4103/1673-5374.153695

Figure 3.

Figure 3

Antioxidant-like protein-1 (AOP-1) immunoreactivity in the hippocampal CA3 region of control and streptozotocin (STZ)-treated rats.

AOP-1 immunoreactivity was decreased in rats after STZ treatment. (A–D) Photomicrographs of immunohistochemistry for AOP-1 immunoreactivity in the hippocampal CA1 region of controls (A) and rats treated with STZ for 2 (B), 3 (C) and 4 weeks (D). AOP-1 immunoreactivity is found in non-pyramidal cells of the CA3 region. SO: Stratum oriens; SP: stratum pyramidale; SR: stratum radiatum. Scale bar: 100 μm. (E) Number of AOP-1-immunoreactive cells per section from each group. Differences between groups were analyzed statistically by one-way analysis of variance followed by Bonferroni's post-hoc analysis (n = 5 per group; *P < 0.05, vs. control group; #P < 0.05, vs. STZ-2W group). The bars indicate the standard error of the mean (SEM). STZ-2W, STZ-3W, and STZ-4W mean treatment with STZ for 2, 3 and 4 weeks, respectively.