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. 2015 Mar;10(3):467–472. doi: 10.4103/1673-5374.153698

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The immunoreactivity of CHOP in the rat hippocampus after paraquat poisoning (immunohistochemical staining, × 40).

(A–C) Reaction products of CHOP were mainly expressed in the nuclei of neuroglial cells (visualized as brown, arrows) in the control (Con), paraquat (PQ), and ulinastatin (UTI), with some expression in the cytoplasm. (D) CHOP immunoreactivity was significantly stronger in the PQ group than in either the Con group or the UTI group. *P < 0.05, vs. the other two groups. Data are expressed as the mean ± SD (n = 6; one-way analysis of variance and Student-Newman-Keuls test).