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. 2015 Mar;10(3):467–472. doi: 10.4103/1673-5374.153698

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The apoptotic cells in the rat hippocampus after paraquat poisoning (TUNEL staining, optical microscope, × 40).

(A–C) TUNEL-positive cells in the control group (Con) were rare. Apoptotic cells are visible in the paraquat (PQ) and ulinastatin (UTI) groups (arrows). Positive cells are visible as brown nuclei, and their reaction products aggregated around the nuclear membrane. The cells were more positive for TUNEL in the PQ group than in either the Con group or the UTI group. *P < 0.05, vs. the other two groups. Data are expressed as the mean ± SD (n = 6; one-way analysis of variance and Student-Newman-Keuls test). TUNEL: Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling.