Table 2.
Serum lipids, hormones, and C-reactive protein (CRP) analyzed by repeated measures analysis of covariance (RM ANCOVA).
| Variablea | Time 1, mean ± SD or median (Q1–Q3) |
Time 2, mean ± SD or median (Q1–Q3) |
RM ANCOVA effects (df = 1,75)b |
||||
|---|---|---|---|---|---|---|---|
| PTSD (n = 63) | Controls (n = 27) | PTSD (n = 63) | Controls (n = 27) | Group, F (p) | Time, F (p) | Interaction, F (p) | |
| Serum lipids | |||||||
| Triglycerides (mmol/L) | 1.54 (1.27–2.29) | 1.89 (1.17–2.95) | 2.11 (1.47–2.97) | 1.94 (1.40–3.05) | 2.64 (0.108) | 0.14 (0.707) | 0.23 (0.631) |
| Total cholesterol (mmol/L) | 5.69 ± 1.05 | 5.86 ± 0.73 | 6.04 ± 1.14 | 5.98 ± 1.14 | 0.39 (0.535) | 2.32 (0.133) | 1.24 (0.269) |
| LDL-C (mmol/L) | 3.26 ± 0.79 | 3.67 ± 0.97 | 3.82 ± 0.97 | 3.76 ± 1.14 | 0.11 (0.737) | 1.48 (0.227) | 5.04 (0.028) |
| HDL-C (mmol/L) | 1.12 ± 0.18 | 1.07 ± 0.21 | 1.10 ± 0.21 | 1.14 ± 0.21 | 0.24 (0.629) | 0.26 (0.612) | 0.13 (0.716) |
| Serum hormones | |||||||
| Cortisol (ng/mL) | 313.89 ± 87.84 | 296.45 ± 63.02 | 200.57 ± 71.61 | 215.12 ± 51.39 | 1.58 (0.212) | 5.19 (0.026) | 1.91 (0.171) |
| DHEA-S (μg/mL) | 1.75 (1.32–3.12) | 1.27 (0.79–1.78) | 1.00 (0.56–1.52) | 0.43 (0.30–0.70) | 8.14 (0.006) | 4.86 (0.031) | 0.04 (0.834) |
| Prolactin (ng/mL) | 5.96 (4.69–7.73) | 11.48 (7.38–15.82) | 5.90 (4.48–8.94) | 10.90 (7.30–12.86) | 5.40 (0.023) | 2.92 (0.092) | 4.06 (0.055) |
| CRP (mg/L) | 1.70 (0.90–3.80) | 1.20 (0.90–2.10) | 2.00 (1.00–3.40) | 1.50 (0.70–2.10) | 0.62 (0.435) | 1.87 (0.175) | 1.78 (0.675) |
DHEA-S, dehydroepiandrosterone-sulfate; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; PTSD, post-traumatic stress disorder; Q1–Q3, interquartile range; SD, standard deviation.
aVariables represented by median (Q1–Q3) were log-transformed.
bStatistically significant (p < 0.05) results are shown in bold.