Table 5.
Combinations of the (GT)n repeat and A(−413)T genotypes
| (GT)n | T(−413)A | N (%) | OR (95% CI) | P value |
|---|---|---|---|---|
| SS | AA | 0 (0.0) | - | - |
| SS | AT | 3 (0.6) | 1.77 (0.15-21.34) | 0.65 |
| SS | TT | 23 (4.3) | 0.63 (0.22-1.84) | 0.40 |
| SM | AA | 3 (0.6) | <0.001 (<0.001- > 999.99) | 1.0 |
| SM | AT | 54 (10.0) | 1.01 (0.46-2.22) | 1.0 |
| SM | TT | 22 (4.1) | 1.12 (0.42-3.37) | 0.75 |
| SL | AA | 2 (0.4) | <0.001 (<0.001- > 999.99) | 1.0 |
| SL | AT | 21 (3.9) | 0.39 (0.09-1.58) | 0.19 |
| SL | TT | 65 (12.1) | 0.70 (0.33-1.50) | 0.36 |
| MM | AA | 37 (6.9) | 0.66 (0.27-1.58) | 0.35 |
| MM | AT | 27 (5.0) | 0.70 (0.24-2.04) | 0.52 |
| MM | TT | 18 (3.4) | 0.59 (0.14-2.45) | 0.47 |
| ML | AA | 9 (1.7) | 1.43 (0.28-7.21) | 0.66 |
| ML | AT | 90 (16.7) | 1.30 (0.66-2.57) | 0.45 |
| ML | TT | 57 (10.6) | 0.71 (0.31-1.62) | 0.42 |
| LL | AA | 2 (0.4) | <0.001 (<0.001- > 999.99) | 0.99 |
| LL | AT | 25 (4.7) | 0.13 (0.02-1.08) | 0.06 |
| LL | TT | 80 (14.9) | Reference | - |
Frequencies of the T(−413)A genotypes combined with the genotypes of the (GT)n repeats. The combinations ML/AT, LL/TT, SL/TT, ML/TT, SM/AT were the most prevalent. No significant association with severity of malaria was found by analysis with logistic regression models, adjusted for age and sex. Significance level p < 0.05.