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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Prostaglandins Other Lipid Mediat. 2014 Aug 22;0:45–51. doi: 10.1016/j.prostaglandins.2014.08.002

Table 3a.

Associations between medications and HETEs

Medication Eicosanoid
20-HETE 19-HETE 15-HETE 12-HETE 8-HETE
Beta-blockers 0.85 p=0.281 (0.64, 1.14) 0.79 p=0.045 (0.63, 1.00) 1.08 p=0.798 (0.61, 1.89) 0.87 p=0.617 (0.50, 1.51) 1.01 p=0.944 (0.75, 1.36)
ACEI 1.01 p=0.959 (0.76, 1.33) 1.07 p=0.546 (0.85, 1.35) 1.16 p=0.557 (0.70, 1.93) 0.83 p=0.471 (0.50, 1.38) 1.02 p=0.905 (0.77, 1.35)
ARB 1.41 p=0.056 (0.99, 2.00) 1.11 p=0.509 (0.82, 1.51) 0.89 p=0.737 (0.47, 1.72) 0.99 p=0.966 (0.52, 1.89) 1.11 p=0.559 (0.78, 1.59)
Eplerenone/spironolactone 1.08 p=0.739 (0.69, 1.70) 0.92 p=0.650 (0.63, 1.33) 0.78 p=0.501 (0.38, 1.60) 1.29 p=0.513 (0.60, 2.76) 1.00 p=0.981 (0.67, 1.50)
Ca channel blocker 0.74 p=0.033 (0.56, 0.98) 0.83 p=0.106 (0.66, 1.04) 1.02 p=0.927 (0.61, 1.73) 0.70 p=0.197 (0.41, 1.20) 0.73 p=0.021 (0.55, 0.95)
Diuretic 0.99 p=0.930 (0.72, 1.36) 1.00 p=0.985 (0.77, 1.30) 0.72 p=0.299 (0.39, 1.34) 0.96 p=0.881 (0.52, 1.74) 0.76 p=0.082 (0.55, 1.04)
Statin 1.37 p=0.031 (1.03, 1.81) 1.17 p=0.185 (0.93, 1.49) 0.73 p=0.205 (0.44, 1.19) 0.68 p=0.144 (0.41, 1.14) 0.97 p=0.831 (0.72, 1.30)
Other immunosuppressive 1.68 p=0.226 (0.72, 3.91) 1.20 p=0.561 (0.65, 2.19) 1.09 p=0.915 (0.24, 4.95) 0.88 p=0.845 (0.26, 3.02) 1.04 p=0.929 (0.47, 2.30)
Steroids 1.39 p=0.171 (0.87, 2.24) 1.17 p=0.430 (0.79, 1.74) 1.08 p=0.848 (0.48, 2.41) 1.07 p=0.868 (0.46, 2.51) 1.18 p=0.463 (0.76, 1.84)