Figure 1.

Appearance of esophagus after 6 month of surgery. C/H show the gross appearance of the intact esophagus. A/F and B/G display the apperance of that suffered from 6 months of reflux due to surgical procedues (A/F, duodenoesophageal reflux; B/G, duodenogastroesophageal reflux). Surgical group rats show abnormally dilated esophagus, and esophageal inner surface displays nodular patches (arrow in G) and ulcers (arrow in F). D/I and E/J show the esophagus of animals fed with exogenous chemicals (D/I, bile acids feeding; E/J, acidic water feeding). The mucosa of these two groups become thick and nodular patches occur (arrow in G).