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Abundance of HMGB1, IL-6, IL-10 and TNF-α both in plasma and sputum of APTB patients. ELISA was performed in concomitantly collected plasma and sputum samples. Plasma and sputum HMGB1 (A), IL-6 (B), IL-10 (C) and TNF-α (D) were significantly increased in APTB patients (n=36) compared to HV (n=32). Data were shown as Mean ± SEM. *, P<0.05; **, P<0.01; ***, P<0.0001.
