Table 3.

Correlation between CD147 and MMP-9^a expressions in type II/III AEG^b tissues and clinicopathological parameters

Clinicopathological indexes	CD147 expression		χ2	P	MMP-9 expression		χ2	P
	-	+-+++			-	+-+++
Age (years)
≤ 50	15	26			12	29
> 50	17	16	1.660	0.198	12	21	0.420	0.517
Gender
Male	24	32			18	38
Female	8	10	0.014	0.906	6	12	0.009	0.925
Tumor length (cm)
< 2	7	8			8	7
2-5	14	24			10	28
> 5	11	10	1.420	0.492	6	15	3.782	0.151
Lymphatic metastasis
+	10	28			5	33
-	22	14	9.119	0.003	19	17	13.242	0.000
Liver metastasis
+	6	0			6	0
-	36	32	3.242	0.072	44	24	1.730	0.188
Abdominal metastasis
+	8	1			8	1
-	34	31	2.949	0.086	42	23	1.162	0.281
Histological differentiation grade
Well	12	7			12	7
Moderately	12	13			10	15
Poorly	8	22	6.659	0.036	7	23	7.752	0.021
TNM Classification
Stage I/II	18	10			15	13
Stage III/IV	14	32	8.126	0.004	9	37	9.185	0.002
Siewert classification
Type II	12	17			11	18
Type III	20	25	0.068	0.795	13	32	0.658	0.417

^aMMP-9, matrix metalloproteinase 9;

^bAEG, adenocarcinoma of esophagogastric junction.