Table 4.
Cerebral oxygen and glucose metabolism at different time points in each group
| PREOP | 5’-AI | PD | 60’PD | POSTOP | |
|---|---|---|---|---|---|
| Group A (Isoflurane) | |||||
| Hb (g/dL) | 130 ± 16 | 101 ± 13 | 103 ± 16 | 106 ± 19 | 108 ± 12 |
| SjvO2 (%) | 58 ± 9 | 59 ± 7 | 62 ± 9 | 64 ± 12 | 67 ± 8 |
| CaO2 (mL/dL) | 165 ± 13 | 143 ± 15 | 147 ± 16 | 151 ± 12 | 139 ± 14 |
| CjvO2 (mL/dL) | 104 ± 14 | 87 ± 13 | 89 ± 17 | 92 ± 15 | 93 ± 18 |
| Da-jvO2 (mL/dL) | 58 ± 18 | 54 ± 16 | 52 ± 10 | 50 ± 13 | 47 ± 14 |
| OEr (%) | 35 ± 14 | 36 ± 12 | 35 ± 8 | 39 ± 12 | 31 ± 11 |
| Glua (mmol/L) | 59.2 ± 5.9 | 50.7 ± 3.2 | 54.9 ± 4.3 | 66.8 ± 7.7 | 68.4 ± 8.2 |
| Da-jvGlu (mmol/L) | 5.7 ± 1.6 | 5.1 ± 0.9 | 5.3 ± 1.2 | 5.4 ± 0.6 | 5.5 ± 0.8 |
| GluER (%) | 0.10 ± 0.05 | 0.11 ± 0.03 | 0.09 ± 0.03 | 0.07 ± 0.05 | 0.05 ± 0.04 |
| Laca (mmol/L) | 1.4 ± 0.6 | 1.3 ± 0.8 | 1.7 ± 0.9 | 2.1 ± 1.2 | 2.4 ± 0.8 |
| Da-jvLac (mmol/L) | -0.10 ± 0.09 | -0.13 ± 0.16 | -0.19 ± 0.20 | -0.23 ± 0.18 | -0.27 ± 0.14 |
| LacPR (%) | -0.08 ± 0.10 | -0.09 ± 0.12 | -0.10 ± 0.07 | -0.11 ± 0.09 | -0.11 ± 0.03 |
| Group B (Sevoflurane) | |||||
| Hb (g/dL) | 131 ± 14 | 104 ± 14 | 106 ± 15 | 108 ± 17 | 110 ± 16 |
| SjvO2 (%) | 57 ± 7 | 63 ± 8 | 66 ± 7 | 67 ± 9 | 68 ± 10 |
| CaO2 (mL/dL) | 164 ± 15 | 150 ± 13 | 153 ± 14 | 155 ± 16 | 142 ± 18 |
| CjvO2 (mL/dL) | 105 ± 17 | 92 ± 20 | 93 ± 20 | 94 ± 18 | 94 ± 20 |
| Da-jvO2 (mL/dL) | 60 ± 15 | 58 ± 17 | 54 ± 12 | 51 ± 11 | 49 ± 12 |
| OEr (%) | 37 ± 12 | 38 ± 13 | 39 ± 9 | 41 ± 10 | 33 ± 10 |
| Glua (mmol/L) | 58.1 ± 5.7 | 53.8 ± 4.6 | 56.9 ± 4.8 | 70.7 ± 9.2 | 71.5 ± 9.8 |
| Da-jvGlu (mmol/L) | 5.8 ± 1.4 | 5.5 ± 0.5 | 5.4 ± 1.6 | 5.3 ± 0.7 | 5.6 ± 0.9 |
| GluER (%) | 0.11 ± 0.03 | 0.12 ± 0.04 | 0.09 ± 0.05 | 0.08 ± 0.03 | 0.06 ± 0.03 |
| Laca (mmol/L) | 1.3 ± 0.7 | 1.6 ± 0.9 | 2.0 ± 0.8 | 2.4 ± 1.1 | 2.7 ± 0.9 |
| Da-jvLac (mmol/L) | -0.11 ± 0.08 | -0.16 ± 0.18 | -0.23 ± 0.15 | -0.27 ± 0.16 | -0.30 ± 0.19 |
| LacPR (%) | -0.07 ± 0.08 | -0.09 ± 0.06 | -0.10 ± 0.05 | -0.11 ± 0.02 | -0.12 ± 0.07 |
| Group C (Desflurane) | |||||
| Hb (g/dL) | 130 ± 13 | 102 ± 17 | 104 ± 16 | 107 ± 19 | 109 ± 15 |
| SjvO2 (%) | 57 ± 12 | 61 ± 9 | 63 ± 10 | 65 ± 8 | 67 ± 9 |
| CaO2 (mL/dL) | 163 ± 17 | 147 ± 12 | 150 ± 15 | 152 ± 14 | 141 ± 16 |
| CjvO2 (mL/dL) | 104 ± 21 | 90 ± 18 | 91 ± 19 | 92 ± 16 | 93 ± 19 |
| Da-jvO2 (mL/dL) | 59 ± 16 | 57 ± 15 | 52 ± 13 | 50 ± 12 | 48 ± 14 |
| OEr (%) | 36 ± 14 | 37 ± 11 | 38 ± 10 | 39 ± 12 | 32 ± 11 |
| Glua (mmol/L) | 58.4 ± 6.2 | 51.6 ± 3.2 | 54.7 ± 4.7 | 68.1 ± 10.2 | 70.7 ± 7.6 |
| Da-jvGlu (mmol/L) | 5.6 ± 1.7 | 5.3 ± 0.7 | 5.5 ± 1.2 | 5.1 ± 0.9 | 5.4 ± 0.7 |
| GluER (%) | 0.10 ± 0.07 | 0.11 ± 0.02 | 0.10 ± 0.03 | 0.09 ± 0.04 | 0.07 ± 0.01 |
| Laca (mmol/L) | 1.3 ± 0.9 | 1.5 ± 0.8 | 1.8 ± 0.7 | 2.2 ± 1.5 | 2.5 ± 0.7 |
| Da-jvLac (mmol/L) | -0.10 ± 0.13 | -0.14 ± 0.12 | -0.21 ± 0.17 | -0.26 ± 0.15 | -0.28 ± 0.13 |
| LacPR (%) | -0.07 ± 0.12 | -0.08 ± 0.07 | -0.09 ± 0.06 | -0.10 ± 0.04 | -0.11 ± 0.05 |