Figure 2.
Effect of IFN-λ1 on DCs costimulatory molecules expression. Data were exhibited as a percentage. The expression of CD80, CD83, CD86 and HLA-DR in healthy control group was higher than not only the routine group but also the combination group both in the immune tolerant phase and the immune clearance phase. **P < 0.01 compared with the immune tolerant and the immune clearance phases. In the routine group, the expression of CD80, CD83, CD86 and HLA-DR in the immune clearance phase showed a significant increase compared with the immune tolerant phase (##P < 0.01). In the combination group, the expression of CD80 and CD83 in the immune clearance phase were significantly increased compared with the immune tolerant phase (##P < 0.01), while the levels of CD86 and HLA-DR were increased in the immune clearance phase, but did not reach statistical significance (P > 0.05). The expression of CD80, CD83, CD86 and HLA-DR in the combination group was higher than the routine group both in the immune tolerant phase and the immune clearance phase. ΔP < 0.01 in comparison with routine group.