Table 7.
Costing information included in the Markov model (CBS, Centraal Buro Satistiek; DBC, Diagnose Behandel Combinatie [Dutch diagnosis treatment code]; PCP, primary care physician; NZa, Nederlandse Zorgautoriteit [Dutch health authority].
| Dose | First pack (28 days) | After 28 days | Data source | Costing year | ||
|---|---|---|---|---|---|---|
| Prucalopride | 1 mg | € 1.95 per day | € 1.62 per day | Shire-Movetis | 2010 | |
| 2 mg | € 2.77 per day | € 2.49 per day | Shire-Movetis | 2010 | ||
| Pack size | Cost per pack | Distribution start (switch)a | Daily dose | Daily cost | Costing year | |
| SOURCE: FARMACOTHERAPEUTISCH KOMPAS | ||||||
| Movicolon® sachets | 1 sachet | € 0.32 | 42% (27%) | 1.5 sachet | € 0.48 | 2010 |
| Bisacodyl | 5 mg | € 0.11 | 8% (17%) | 7.5 mg | € 0.17 | 2010 |
| Forlax® | 10 g | € 0.61 | 15% (7%) | 10 g | € 0.61 | 2010 |
| Metamucil® | 1 sachet | € 0.30 | 18% (23%) | 2 sachets | € 0.60 | 2010 |
| Lactulose | 10 g | € 0.23 | 17% (0%) | 10 mg | € 0.23 | 2010 |
| Magnesium oxide | 500 mg | € 0.03 | 0% (26%) | 3.5 g | € 0.21 | 2010 |
| Prescription rule | € 6.35 | |||||
| Cost/unit | Data source | Costing year | ||||
| PCP | € 28.00 | Costing manual | 2009 | |||
| Specialist | € 72.00 | Costing manual | 2009 | |||
| PCP telephone call | € 14.00 | Costing manual | 2009 | |||
| Nurse | € 10.00 | Costing manual | 2009 | |||
| Nurse telephone call | € 0.00 | Costing manual | 2009 | |||
| Dietician | € 27.00 | Costing manual | 2009 | |||
| DBC: polyclinic for constipation | € 195.89 | DBC 1337101b (NZa tarieven) | 2010 | |||
| DBC: hospitalization for constipation | € 3102.00 | DBC 141508 (NZa tarieven) | 2010 | |||
| Inflation rate | Data source | Costing year | ||||
| 2009 | 1.2% | CBS | 2009 | |||
| 2010 | 1.3% | CBS | 2010 | |||
a
Distribution of laxatives at start (and after switching) of therapy.
b
See Supplementary Material.