Figure 9. Ampicillin administration early after virulent L. monocytogenes prenatal infection protects against fetal wastage.
Percentage of resorbed fetuses, number of live pups, and frequency of L. monocytogenes recovery from each concepti 5 days after virulent L. monocytogenes (104 CFU) infection initiated midgestation (E11.5) among female C57BL/6 mice bearing allogeneic pregnancies after mating with BALB/c males that were administered ampicillin in the drinking water beginning 12 or 24 hours after infection compared with controls maintained on autoclaved drinking water without supplementation. Each symbol indicates the data from a single mouse, and these results, containing 7–8 mice per group, are representative of 3 independent experiments, each with similar results. Error bars represent mean ± 1 SEM.