Table 2.
Association of IGF-1, IGFBP-1, IGFBP-3, and Age With Leukocyte Telomere Length Among 551 Men and Women 65 Years and Older
β | SE (β) | p Value | |
Model 1 | |||
IGF-1 (per SD) | .06 | .04 | .09 |
IGFBP-1 (per SD) | .03 | .03 | .22 |
IGFBP-3 (per SD) | −.02 | .04 | .54 |
Age (per SD) | −.09 | .03 | <.01 |
Model 2 | |||
IGF-1 (per SD) | .08 | .04 | .04 |
IGFBP-1 (per SD) | .04 | .03 | .23 |
IGFBP-3 (per SD) | −.04 | .04 | .30 |
Age (per SD) | −.09 | .03 | <.01 |
Note: β represents change in leukocyte telomere length associated with 1 SD change in IGF-1, IGFBP-1, or IGFBP-3. Model 1: Adjusted for IGF-1, IGFBP-1, IGFBP-3, age, race, sex, and laboratory batch. Model 2: Adjusted for covariates in Model 1 plus smoking status (ever vs never), body mass index, hypertension, diabetes, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol. IGF-1 = insulin-like growth factor-1; IGFBP = insulin-like growth factor–binding protein.