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. 2015 Mar 14;17(1):60. doi: 10.1186/s13075-015-0569-6

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© Arkesteijn et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Comparison of the effect of notochordal cells (NCs) on nucleus pulposus cells (NPCs) and mesenchymal stromal cells (MSCs). Depiction of the (A) DNA content and (B) glycosaminoglycan (GAG) content normalized to DNA (GAG/DNA) and the relative gene expression of (C) NC marker brachyury; (D) aggrecan; (E) collagen, type II, α1 (COL2A1); and (F) collagen, type I, α1 (COL1A1). White bar = day 1, gray bar = day 15, black bar = day 28. ^$ P < 0.05, significant difference in the increase in gene expression in time between groups. ^# P < 0.001, significant difference in the increase in gene expression in time between groups. Only relevant comparisons are displayed.