Table 2.
Univariate and multivariate analyses of CPC factors associated with the overall survival
| Variables | Univariate analysis
|
Multivariate analysis
|
||||||
|---|---|---|---|---|---|---|---|---|
| Significance | HR | 95% CI for HR
|
Significance | HR | 95% CI for HR
|
|||
| Lower | Upper | Lower | Upper | |||||
| AURKB | 0.0465 | 1.8741 | 1.0130 | 3.4672 | 0.0546 | 1.8573 | 0.9912 | 3.4804 |
| Borealin | 0.0789 | 1.7486 | 0.9404 | 3.2515 | 0.1950 | 1.5187 | 0.8098 | 2.8483 |
| INCENP | 0.0404 | 1.9362 | 1.0325 | 3.6310 | 0.0211 | 2.1346 | 1.1243 | 4.0526 |
| Survivin | 0.0072 | 2.4002 | 1.2709 | 4.5329 | 0.0345 | 2.0602 | 1.0576 | 4.0135 |
| 4-CPC-gene prognostic model | 0.0013 | 2.8915 | 1.5187 | 5.5052 | 0.0082 | 2.4398 | 1.2631 | 4.7127 |
Abbreviations: AURKB, aurora B kinase; CI, confidence interval; CPC, chromosomal passenger complex; INCENP, inner centromere protein; HR, hazard ratio.