Table 3. Endometrial Cancer Risk Stratified by Baseline Body Mass Index, California Teachers Study Cohort, 1995-2011.
Per unit increase | RRa | ||||||||||
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Dietary pattern | RRa | 95% CI | P-intb | Q1 | Q2 | Q3 | Q4 | Q5 | 95%CIc | P-trendd | P-inte |
BMI <25, 427 cases | |||||||||||
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Plant-based | 0.93 | 0.83, 1.05 | 1.0 | 0.91 | 0.73 | 1.03 | 0.78 | 0.56, 1.10 | 0.35 | ||
High protein/high fat | 0.86 | 0.73, 1.01 | 1.0 | 0.97 | 0.81 | 0.81 | 0.90 | 0.61, 1.33 | 0.42 | ||
High carbohydrate | 0.80 | 0.67, 0.97 | 1.0 | 1.04 | 0.87 | 0.80 | 0.82 | 0.51, 1.31 | 0.23 | ||
Ethnic | 1.00 | 0.91, 1.11 | 1.0 | 0.94 | 1.20 | 1.06 | 1.07 | 0.78, 1.46 | 0.58 | ||
Salad and wine | 1.11 | 1.00, 1.23 | 1.0 | 1.70 | 1.38 | 1.44 | 1.73 | 1.14, 2.61 | 0.05 | ||
BMI ≥25, 510 cases | |||||||||||
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Plant-based | 1.01 | 0.91, 1.12 | 0.97 | 1.0 | 1.04 | 1.01 | 1.14 | 1.03 | 0.75, 1.42 | 0.76 | 0.69 |
High protein/high fat | 1.03 | 0.89, 1.18 | 0.78 | 1.0 | 1.05 | 1.19 | 1.24 | 1.29 | 0.89, 1.88 | 0.14 | 0.43 |
High carbohydrate | 0.99 | 0.84, 1.16 | 0.80 | 1.0 | 0.93 | 0.88 | 0.97 | 1.00 | 0.67, 1.50 | 0.96 | 0.89 |
Ethnic | 1.04 | 0.95, 1.14 | 0.37 | 1.0 | 0.82 | 0.79 | 0.97 | 0.98 | 0.75, 1.30 | 0.78 | 0.31 |
Salad and wine | 0.95 | 0.87, 1.05 | <0.01 | 1.0 | 1.09 | 0.99 | 1.11 | 0.98 | 0.72, 1.33 | 0.84 | 0.01 |
BMI, body mass index; CI, confidence interval; P-int, P-interaction; Q, quintile; RR, relative risk
Adjusted for race and its interaction with time-dependent age, age at menarche, gravidity and age at last pregnancy and its interaction with time-dependent age, oral contraceptive use, physical activity, smoking status, height, caloric intake, the other four dietary patterns, and the following time-dependent exposures: BMI, menopausal status/hormone therapy use, and their interaction; age was the time metric and the model was stratified by age at baseline
P-interaction for dietary pattern modeled per unit increase
Associated with the highest quintile
P-trend across quintiles
P-interaction for dietary pattern modeled in quintiles