Fig. 6.

Steady-state values of bacteria and phagocyte levels under anti-virulence treatment when (a) natural clearance (ψ) and (b) baseline immune response (γ) are varied. The bacteria can be cleared from the infection but only when these host-specific parameters are sufficiently strong. We note that the critical values of ψ and γ above which all bacteria will be cleared are lower in the discontinuous model stated in (1)–(5) (around $\psi \approx 12$ and $\gamma \approx 0.01$) than in these figures due to the rule that S or R can only degrade when $S<1$ or $R<1$ in the time-dependent solutions (recall that this rule is removed to generate steady-state diagrams from continuous equations in XPPAUT).