Skip to main content
. Author manuscript; available in PMC: 2015 Apr 14.
Published in final edited form as: Vaccine. 2010 Feb 23;28(8):1942–1951. doi: 10.1016/j.vaccine.2009.10.095

Table 1. Study design and immunization groups.

Groups of Chinese rhesus macaques (n=5) were immunized with RNA- and codon-optimized DNA constructs: SIV Gag, Pol, Env +/- rhesus CCL27 (1.0 mg each construct). A total of 4 immunizations were given intramuscularly with electroporation 6 weeks apart. The naïve group received saline and electroporation. 10 weeks later macaques were challenged given a high dose intrarectal challenge with SIVmac251.

graphic file with name nihms160594u1.jpg
Group Name Antigenic Construct Adjuvant
Naive Saline Saline
DNA 1mg pGag Saline
1mg pPol
1mg pEnv
CCL27 1mg pGag 1mg pCCL27
1mg pPol
1mg pEnv