Table 2.

Characteristics and main outcomes of the study patients during admission to the intensive care unit

Characteristic	PMV	Non-PMV	p value	OR (95% CI)
	(N = 218)	(N = 1,979)
Severity at ICU: day 1
APACHE II*,**	21.4 ± 7.2	19.4 ± 8.3	0.001
GCS	12.0 ± 4.0	11.5 ± 4.5	0.12
SOFA	5.3 ± 3.7	5.1 ± 3.5	0.42
TISS	26.5 ± 7.4	26.1 ± 7.8	0.47
Presence of infection	134 (61.4)	1004 (50.7)	< 0.001	1.94 (1.40 - 2.69)
Diagnosis of severe sepsis	48 (22.0)	354 (17.9)	0.01	1.54 (1.07 - 2.21)
During ICU stay
Organ support during ICU stay
Vasoactive drug use	183 (83.9)	1332 (67.3)	< 0.001	2.54 (1.74 - 3.69)
RRT	54 (24.8)	235 (11.9)	< 0.001	2.44 (1.74 - 3.42)
Parenteral nutrition support	27 (12.4)	131 (6.7)	0.002	1.98 (1.27 - 3.07)
Tracheotomy need	151 (69.2)	168 (8.5)	< 0.001	24.3 (17.4 - 33.7)
Need for unscheduled surgery	62 (28.4)	291 (14.7)	< 0.001	2.3 (1.67 - 3.17)
DNR decision	15 (6.9)	138 (7.0)	0.93	0.98 (0.56 - 1.71)
At ICU discharge
Severity at ICU discharge
GCS	13.5 ± 2.52	14.2 ± 1.79	0.01
SOFA	3.01 ± 4.03	2.64 ± 4.18	0.21
TISS	10.8 ± 11.07	10.6 ± 10.12	0.78
ICU death	113 (51.8)	744 (37.6)	< 0.001	1.78 (1.35 - 2.36)
Hospital death	142 (65)	911 (44.9)	< 0.001	2.23 (1.67 - 2.99)

PMV - prolonged mechanical ventilation; OR - odds ratio; 95% CI - 95% confidence interval; APACHE - Acute Physiology and Chronic Health Evaluation; GCS - Glasgow Coma Score; SOFA - Sepsis-related Organ Failure Assessment; TISS - Therapeutic Intervention Scoring System; ICU - intensive care unit; RRT - renal replacement therapy; DNR - do not resuscitate. Results are expressed as number (percentage) or mean ± standard deviation. Data obtained by univariate analysis;

^*only in patients without sedation;

^**score applied and calculated in neurological and no neurological patients.