Table 1.

Mean blood pharmacokinetics of H1PV in Wistar rats after a single intracerebral or intravenous administration of 7.96× 107 pfu

	Route	Maximal concentration (no. VG/µL)	Time at maximal concentration (h)	AUC0–t (no. VG × h/µL)	Absolute bioavailability (%)
Male	IC	8.78 × 104	2.00	4.77 × 105	42
	IV	1.64 × 106	0.25	1.13 × 106	not done
Female	IC	1.53 × 105	0.50	5.55 × 105	97