Table 1.

The main features of the included studies for miR-155 in the diagnosis of cancers. DLBCL: diffuse large B cell lymphoma; AML: acute myeloid leukemia; QUADAS: quality assessment for studies of diagnostic accuracy.

Author	Year	Ethnicity	Patients (control)	Cancer type	Sample	Test method	MicroRNA profiling	QUADAS scores
Mar-Aguilar et al. [18]	2013	Caucasian	61 (10)	Breast cancer	Serum	RT-qPCR	miR-155	12
Sun et al. [17]	2012	Asian	103 (55)	Breast cancer	Serum	RT-qPCR	miR-155	13
Zhao et al. [19]	2012	Asian	20 (10)	Breast cancer	Serum	RT-qPCR	miR-155	12
Fang et al. [12]	2012	Asian	75 (77)	DLBCL	Serum	RT-qPCR	miR-155	12
Xie et al. [20]	2012	Asian	45 (30)	AML	Serum	RT-qPCR	miR-155	8
Pan et al. [21]	2014	Asian	30 (26)	Pancreatic cancer	Plasma	RT-qPCR	miR-155	8
Wang et al. [22]	2009	Asian	30 (29)	Pancreatic cancer	Plasma	RT-qPCR	miR-155	12
Abd-El-Fattah et al. [23]	2013	Caucasian	65 (37)	Lung cancer	Serum	RT-qPCR	miR-155	11
Gao et al. [24]	2014	Asian	36 (32)	Lung cancer	Serum	RT-qPCR	miR-155	9
Tang et al. [25]	2013	Asian	96 (92)	Lung cancer	Plasma	RT-qPCR	Single miR-155 and paneled miRNAs	12
Liu et al. [26]	2012	Asian	60 (60)	Esophageal cancer	Plasma	RT-qPCR	miR-155	9
Yang et al. [27]	2015	Asian	20 (20)	Rectal cancer	Tissue	RT-qPCR	miR-155	12
Gombos et al. [28]	2013	Caucasian	40 (40)	Oral squamous cell cancer	Tissue	RT-qPCR	miR-155	9
Häusler et al. [29]	2010	Caucasian	24 (15)	Ovarian cancer	Whole blood	RT-qPCR	More than thirty paneled miRNAs involved miR-155	11
Heneghan et al. [2]	2010	Caucasian	83 (63)	Breast cancer	Whole blood	RT-qPCR	Three paneled miRNAs involved miR-155	12
Roa et al. [30]	2012	Caucasian	24 (6)	Lung cancer	Sputum	RT-qPCR	Five paneled miRNAs involved miR-155	12
Zheng et al. [31]	2011	Asian	74 (68)	Lung cancer	Plasma	RT-qPCR	Three paneled miRNAs involved miR-155	12