Table 2.
Analyses | Spearman correlation coefficient | Cochran's Q test | I 2 test (%) | Heterogeneity | |
---|---|---|---|---|---|
Threshold effect | Nonthreshold effect | ||||
Single miR-155 | −0.363a
P = 0.203 |
46.73b
P = 0.0000 |
72.2 | No | Yes |
Panel miR-155 | −0.606a
P = 0.037 |
35.98b
P = 0.0002 |
69.4 | Yes | Yes |
Serum-based | −0.571a
P = 0.180 |
16.06b
P = 0.0134 |
62.6 | No | Yes |
Plasma-based | 0.359a
P = 0.553 |
10.42b
P = 0.0340 |
61.6 | No | Yes |
Asian | −0.409a
P = 0.212 |
25.23b
P = 0.0049 |
60.4 | No | Yes |
Caucasian | 0.500a
P = 0.667 |
2.16b
P = 0.3394 |
7.4 | No | No |
Overall | −0.385a
P = 0.052 |
85.38b
P = 0.0000 |
70.7 | No | Yes |
Outliers excluded | −0.418a
P = 0.156 |
46.76b
P = 0.0000 |
70.3 | No | Yes |
aThe value of sensitivity and (1 − specificity); b Q value.