Table 3.
Effect of AGE and SAC on MDA, GSHPx, GSH, and GSSG.
| Treatment | MDA (nmol/mL) | GSHPx (U/mg protein) | GSH (nmol/mL) | GSSG (nmol/mL) |
|---|---|---|---|---|
| NFD control | 0.48 ± 0.02 | 0.46 ± 0.03 | 5.09 ± 0.02 | 4.54 × 10−2 ± 0.3 × 10−2 |
| NFD + AGE-L | 0.37 ± 0.01∗∗ | 0.39 ± 0.02∗∗∗ | 4.08 ± 0.37∗∗ | 3.93 × 10−2 ± 0.3 × 10−2∗ |
| NFD + AGE-H | 0.28 ± 0.02∗∗∗ | 0.29 ± 0.05∗∗∗ | 3.81 ± 0.22∗∗∗ | 2.98 × 10−2 ± 0.4 × 10−2∗∗∗ |
| NFD + SAC-L | 0.41 ± 0.04∗ | 0.41 ± 0.02∗∗ | 4.78 ± 0.24∗ | 4.10 × 10−2 ± 0.5 × 10−2∗ |
| NFD + SAC-H | 0.33 ± 0.03∗∗ | 0.31 ± 0.03∗∗∗ | 4.15 ± 0.38∗∗ | 3.28 × 10−2 ± 0.6 × 10−2∗∗∗ |
| HFD control | 0.81 ± 0.09aaa | 0.71 ± 0.04aaa | 6.87 ± 0.27aaa | 6.88 × 10−2 ± 0.2 × 10−2aaa |
| HFD + AGE-L | 0.62 ± 0.01∗∗∗ | 0.48 ± 0.08∗∗ | 5.59 ± 0.29∗∗ | 5.02 × 10−2 ± 0.6 × 10−2∗∗ |
| HFD + AGE-H | 0.41 ± 0.09∗∗∗ | 0.33 ± 0.04∗∗∗ | 4.60 ± 0.54∗∗∗ | 3.97 × 10−2 ± 0.3 × 10−2∗∗∗ |
| HFD + SAC-L | 0.63 ± 0.05∗∗ | 0.58 ± 0.06∗∗ | 5.984 ± 0.51∗∗ | 5.99 × 10−2 ± 0.3 × 10−2 |
| HFD + SAC-H | 0.47 ± 0.10∗∗∗ | 0.39 ± 0.05∗∗∗ | 5.13 ± 0.16∗∗ | 4.82 × 10−2 ± 0.1 × 10−2∗∗∗ |
Values are expressed as mean ± SEM of eight rats. AGE-L: low dose of AGE, 2 mL/kg; AGE-H: high dose of AGE, 5 mL/kg; SAC-L: low dose of SAC, 13.1 mg/kg; and SAC-H: high dose of SAC, 32.76 mg/kg.
Symbols represent statistical significance.
∗∗∗ P < 0.001; ∗∗ P < 0.01 and ∗ P < 0.05 NFD fed versus NFD control and HFD fed versus HFD control respectively. aaa P < 0.001 NFD control versus HFD control.