Table 4.
Effect of AGE and SAC on SOD, CAT, TBARS, FRAP, and total SH groups assay.
| Treatment | SOD (unit/g tissue) |
CAT (unit/g tissue) |
TBARS (nmol/g tissue) |
FRAP value (µmol/g tissue) |
Total sulfhydryl (µmol/g tissue) |
|---|---|---|---|---|---|
| NFD control | 78.5 ± 1.8 | 77.3 ± 1.5 | 32.91 ± 1.3 | 3.93 ± 0.6 | 0.69 ± 0.04 |
| NFD + AGE-L | 84.1 ± 1.2 | 83.6 ± 2.4∗ | 28.11 ± 1.4∗ | 4.89 ± 0.5∗ | 0.78 ± 0.08∗ |
| NFD + AGE-H | 92.4 ± 1.4∗ | 97.2 ± 1.9∗ | 22.43 ± 2.1∗∗∗ | 5.69 ± 0.4∗∗∗ | 0.86 ± 0.02∗∗ |
| NFD + SAC-L | 81.1 ± 1.2 | 87.9 ± 1.9∗ | 29.43 ± 2.1 | 4.10 ± 0.1∗ | 0.71 ± 0.01∗ |
| NFD + SAC-H | 89.5 ± 1.1∗ | 93.0 ± 1.1∗ | 24.22 ± 1.7∗∗ | 5.11 ± 0.4∗∗∗ | 0.81 ± 0.03∗∗ |
| HFD control | 41.2 ± 1.3aaa | 40.1 ± 1.6aaa | 47.21 ± 1.1aaa | 2.91 ± 0.7aaa | 0.31 ± 0.05aaa |
| HFD + AGE-L | 62.0 ± 1.6∗∗∗ | 68.7 ± 1.5∗∗ | 35.89 ± 1.9∗∗∗ | 3.96 ± 0.4∗∗∗ | 0.45 ± 0.03∗ |
| HFD + AGE-H | 73.1 ± 1.3∗∗∗ | 80.4 ± 1.9∗∗∗ | 24.79 ± 1.6∗∗∗ | 4.23 ± 0.3∗∗∗ | 0.61 ± 0.02∗∗∗ |
| HFD + SAC-L | 58.2 ± 1.5∗∗ | 59.3 ± 1.1∗∗ | 38.88 ± 1.7∗∗ | 3.83 ± 0.2∗ | 0.38 ± 0.03∗ |
| HFD + SAC-H | 70.1 ± 1.3∗∗∗ | 71.2 ± 1.2∗∗∗ | 29.66 ± 1.4∗∗∗ | 4.02 ± 0.6∗∗∗ | 0.58 ± 0.01∗∗∗ |
Values are expressed as mean ± SEM of eight rats. AGE-L: low dose of AGE, 2 mL/kg; AGE-H: high dose of AGE, 5 mL/kg; SAC-L: low dose of SAC, 13.1 mg/kg; and SAC-H: high dose of SAC, 32.76 mg/kg.
Symbols represent statistical significance.
∗∗∗ P < 0.001; ∗∗ P < 0.01 and ∗ P < 0.05 NFD fed versus NFD control and HFD fed versus HFD control respectively. aaa P < 0.001 NFD control versus HFD control.