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. Author manuscript; available in PMC: 2016 Aug 27.
Published in final edited form as: Neuroscience. 2014 Oct 14;302:151–164. doi: 10.1016/j.neuroscience.2014.10.004

Table 2.

Social defeat increased E-selectin mRNA expression in the CTX-C, CTX-R, HPC, and BG after RSD in an exposure-dependent manner

Reg mRNA Control Social Defeat
1 d 3 d 6 d
CTX-C E-Selectin 1.01 ± 0.06a 6.67 ± 2.58a,b 8.52 ± 2.15b 65.30 ± 13.73c
P-Selectin 1.01 ± 0.04 1.09 ± 0.02 1.05 ± 0.04 1.10 ± 0.04
PECAM-1 1.00 ± 0.05 0.83 ± 0.04 1.35 ± 0.04 0.85 ± 0.04
CTX-R E-Selectin 1.06 ± 0.16a 3.68 ± 1.21b 6.64 ± 1.12b 53.03 ± 9.51c
P-Selectin 1.00 ± 0.04 1.10 ± 0.04 1.05 ± 0.08 1.25 ± 0.10
PECAM-1 1.04 ± 0.15 0.97 ± 0.07 1.49 ± 0.14 1.27 ± 0.08
HPC E-Selectin 1.07 ± 0.15a 11.95 ± 4.67b 36.95 ± 8.63b 211.37 ± 63.77c
P-Selectin 1.02 ± 0.07 1.17 ± 0.11 1.25 ± 0.11 0.97 ± 0.05
PECAM-1 1.00 ± 0.02 0.81 ± 0.10 1.44 ± 0.05 1.04 ± 0.04
BG E-Selectin 1.04 ± 0.12a 4.82 ± 1.95a,b 5.72 ± 1.13b 71.79 ± 20.86c
P-Selectin 1.00 ± 0.02 1.14 ± 0.05 1.03 ± 0.06 1.05 ± 0.04
PECAM-1 1.00 ± 0.05 0.86 ± 0.07 1.44 ± 0.11 1.34 ± 0.15

Male C57BL/6 mice were subjected to one, three, or six cycles of social defeat (RSD) or left undisturbed as controls (CON). Immediately following the final cycle of RSD, brains were removed, dissected, and frozen in liquid nitrogen. E-selectin, P-selectin, and PECAM-1 mRNA levels were determined in the CTX-C, CTX-R, HPC, and BG (n = 3–6). Values represent average fold change compared to control. Means with different letters (a, b, or c) are significantly different (p < 0.05) from each other.