Western blot. BRS-3 transfected NCI-H1299 cells were treated with 0.1 μM BA1 for 2 min in the presence or absence of varying doses of ML-18 and the P-FAK and FAK (A), P-ERK and ERK (C) as well as P-EGFR and EGFR (E) is indicated. By densitometry analysis, the mean % ± S.D. of 3 determinations is indicated for P-FAK (B), P-ERK (D) and P-EGFR (F); p < 0.05, *; p < 0.01, ** relative to the no additions control; p < 0.05, a; p < 0.01, aa relative to BA1 using the Student's t-test. This experiment is representative of 3 others.