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. 2015 Apr;31(4):521–528. doi: 10.1016/j.cjca.2015.01.019

Table 1.

Noninvasive imaging to screen for PH

First author Technique Number of patients Study population/cause Functional parameter/variable Screening for PH
Sensitivity
(95% CI), %
Specificity
(95% CI), %
Denton et al.24 TTE 33 CTD (SSc) sPAP 90 75
Parent et al.25 TTE 385 Sickle cell disease Tricuspid regurgitation jet velocity 100 80
Rajaram et al.26 TTE 81 CTD Tricuspid gradient 86 82
Wang et al.27 TTE 123 CHD sPAP 89 84
Kuriyama et al.28 CT 23 Suspected PH MPAD 69 100
Perez-Enguix et al.29 CT 71 Candidates for LTX MPAD 66 86
Rajaram et al.26 CT 81 CTD Ventricular mass index 85 82
Stevens et al.30 MRI 100 Suspected PH PVR 92.5 85.2
Rajaram et al.26 MRI 81 CTD RV mass index 85 82

CHD, congenital heart disease; CT, computed tomography; CTD, connective tissue disease; LTX, lung transplantation; MPAD, main pulmonary artery diameter; MRI, magnetic resonance imaging; PH, pulmonary hypertension; PVR, pulmonary vascular resistance; RV, right ventricular; sPAP, systolic pulmonary artery pressure; SSc, systemic sclerosis/scleroderma; TTE, transthoracic echocardiography.