Table 1.
First author | Technique | Number of patients | Study population/cause | Functional parameter/variable | Screening for PH |
|
---|---|---|---|---|---|---|
Sensitivity (95% CI), % |
Specificity (95% CI), % |
|||||
Denton et al.24 | TTE | 33 | CTD (SSc) | sPAP | 90 | 75 |
Parent et al.25 | TTE | 385 | Sickle cell disease | Tricuspid regurgitation jet velocity | 100 | 80 |
Rajaram et al.26 | TTE | 81 | CTD | Tricuspid gradient | 86 | 82 |
Wang et al.27 | TTE | 123 | CHD | sPAP | 89 | 84 |
Kuriyama et al.28 | CT | 23 | Suspected PH | MPAD | 69 | 100 |
Perez-Enguix et al.29 | CT | 71 | Candidates for LTX | MPAD | 66 | 86 |
Rajaram et al.26 | CT | 81 | CTD | Ventricular mass index | 85 | 82 |
Stevens et al.30 | MRI | 100 | Suspected PH | PVR | 92.5 | 85.2 |
Rajaram et al.26 | MRI | 81 | CTD | RV mass index | 85 | 82 |
CHD, congenital heart disease; CT, computed tomography; CTD, connective tissue disease; LTX, lung transplantation; MPAD, main pulmonary artery diameter; MRI, magnetic resonance imaging; PH, pulmonary hypertension; PVR, pulmonary vascular resistance; RV, right ventricular; sPAP, systolic pulmonary artery pressure; SSc, systemic sclerosis/scleroderma; TTE, transthoracic echocardiography.