Table 2.
Patient Comorbidities
| Comorbidity | Patients | P Valuea | |
|---|---|---|---|
| HPV Negative (n = 51) | HPV Positive (n = 111) | ||
| COPD, No. (%) | 6 (12) | 8 (7) | .37 |
| Tobacco use, mean, pack-years | 46.8 | 25.7 | <.001 |
| Alcohol use, No. (%) | <.001 | ||
| Heavy | 24 (47) | 18 (16) | .02b |
| Moderate | 15 (29) | 34 (31) | .001b |
| Rare | 6 (12) | 35 (32) | .23b |
| None | 6 (12) | 24 (22) | <.001b |
| Marijuana use, No. (%) | 24 (47) | 26 (23) | .003 |
| Diabetes mellitus, No. (%) | 5 (10) | 10 (9) | >.99 |
| Major depressive disorder, No. (%) | 5 (10) | 10 (9) | >.99 |
| Anxiety disorder, No. (%) | 6 (12) | 7 (6) | .35 |
| Never smoker, No. (%) | 6 (12) | 60 (54) | <.001 |
Abbreviations: COPD, chronic obstructive pulmonary disease; HPV, human papillomavirus.
a
Univariate analysis using Fisher exact test for categorical data and unpaired t test for continuous data unless otherwise indicated.
b
Multivariate analysis (controlling for diabetes mellitus, marijuana use, COPD, and smoking history).