Table 2.

Pain free rate at 2 hours and headache recurrence rate at 24 hours and 48 hours for all migraine with aura attacks

		Rizatriptan	zolmitriptan	Almotriptan	Frovatriptan	Significance
		(n = 28)	(n = 24)	(n = 8)	(n = 57)
Baseline headache intensity1
	mean	2.4 +/− 0.5	2.2 +/− 0.6	2.3 +/− 0.7	2.1 +/− 0.7	ns
	median	2	2	2	2	ns
Pain free at
	2 hours	10.7%	25.0%	12.5%	29.8%	p < 0.052
	4 hours	35.7%	50.0%	25.0%	50.9%	ns
Recurrence at
	24 hours	42.9%	37.5%	37.5%	26.3%	p < 0.053
	48 hours	89.3%	91.7%	87.5%	66.7%	p < 0.014

¹Headache intensity graded as 0 = none; 1 = mild; 2 = moderate; 3 = severe.

²p < 0.05 for comparison between frovatriptan and rizatriptan.

³only for comparison between frovatriptan and rizatriptan.

⁴post-hoc analysis: p = 0.025 for frovatriptan versus rizatriptan; p = 0.019 for frovatriptan versus zolmitriptan; p = 0.232 for frovatriptan versus almotriptan.

Data are shown as mean (+/− SD), or frequency in %. Statistical comparison by ANOVA or Chi²-test (ns denotes not significant).