Supplementary Table 5. Subgroup analyses for comparing postoperative sexual functions between conventional and nerve sparing radical surgery for cervical cancer.
| Category | No. of studies | OR | 95% CI | Heterogeneity | Model used | |
|---|---|---|---|---|---|---|
| p-value | I2 | |||||
| Decrease of sexual interest | ||||||
| Study design | ||||||
| Prospective | 2 | 0.305 | 0.043-2.170 | 0.055 | 72.839 | Random effects |
| Retrospective | 3 | 0.774 | 0.467-1.281 | 0.461 | <0.001 | Fixed effect |
| Quality of study (NOS) | ||||||
| ≥ 8 | 4 | 0.480 | 0.194-1.185 | 0.011 | 73.057 | Random effects |
| Surgical approach | ||||||
| Laparotomy | 3 | 0.911 | 0.532-1.560 | 0.967 | <0.001 | Fixed effect |
| Radicality | ||||||
| Type III or C | 4 | 0.786 | 0.484-1.277 | 0.659 | <0.001 | Fixed effect |
| Follow-up for evaluating dysfunctions (mo) | ||||||
| 12 | 4 | 0.440 | 0.166-1.166 | 0.020 | 69.574 | Random effects |
| Adjustment for potential confounding factors | ||||||
| Age, adjuvant treatment, FIGO stage | 4 | 0.480 | 0.194-1.185 | 0.011 | 73.057 | Random effects |
| Age, adjuvant treatment, extent of lymphadenectomy, FIGO stage | 3 | 0.378 | 0.112-1.269 | 0.017 | 75.327 | Random effects |
| Dyspareunia | ||||||
| Surgical approach | ||||||
| Laparotomy | 2 | 0.763 | 0.408-1.426 | 0.449 | <0.001 | Fixed effect |
| Radicality | ||||||
| Type III or C | 2 | 0.711 | 0.389-1.298 | 0.530 | <0.001 | Fixed effect |
| Follow-up for evaluating dysfunctions (mo) | ||||||
| 12 | 2 | 0.504 | 0.223-1.138 | 0.754 | <0.001 | Fixed effect |
| Adjustment for potential confounding factors | ||||||
| Age, adjuvant treatment, extent of lymphadenectomy, FIGO stage | 3 | 0.759 | 0.350-1.648 | 0.467 | 75.327 | Fixed effect |
CI, confidence interval; FIGO, International Federation of Gynecology and Obstetrics; NOS, the Newcastle-Ottawa Scale; OR, odds ratio.