Table 3. Multivariate analysis for disease-free survival with clinicopathologic prognostic factors.
| Factor | Hazard ratio | 95% Confidence interval | p-value |
|---|---|---|---|
| HPV viral load | |||
| >Median | 1.00 | ||
| ≤Median | 2.39 | 1.11-5.16 | 0.027 |
| Histologic type | |||
| Squamous cell carcinoma | 1.00 | ||
| AD/ASC | 0.97 | 0.29-3.34 | 0.970 |
| Others* | 32.62 | 8.55-124.42 | <0.001 |
| Lymph node metastasis | |||
| Negative | 1.00 | ||
| Positive | 4.42 | 1.99-9.81 | <0.001 |
| Depth of stromal invasion | |||
| ≤Two-thirds | 1.00 | ||
| >Two-thirds | 1.35 | 0.58-3.16 | 0.490 |
| Parametrial involvement | |||
| Negative | 1.00 | ||
| Positive | 1.72 | 0.49-5.99 | 0.394 |
AD/ASC, adenocarcinoma/adenosquamous carcinoma; HPV, human papillomavirus.
*Neuroendocrine carcinoma and sarcomatoid carcinoma.