Table 2. Comparision of major types of CLE.

Disease features	SCLE	ACLE	Classic DLE
Clinical features of skin lesions
Induration	0	0	+++
Dermal atrophy	0	0	+++
Pigment changes	++	+	+++
Follicular plugging	0	0	+++
Hyperkeratosis	++	+	+++
Histopathology
Thickened basement membrane	+	0	+++
Lichenoid infiltrate	++	+	+++
Periappendageal inflammation	+	0	+++
Lupus band
Lesional	++	++	+++
Non lesional	+	++	0
ANA	++	+++	+
Ro/SS-A antibodies
By immunodiffusion	+++	+	0
By ELISA	+++	++	+
Anti double-stranded DNA antibodies	+	+++	0
Hypocomplementemia	+	+++	+
Risk for developing SLE	++	+++	+

+++, strong association; ++, moderate association; +, weak association; 0, no association. Source: Dermatology in General Medicine by Fitzpatrick (16,17). CLE, cutaneous lupus erythematosus; SCLE, subacute cutaneous lupus erythematosus; ACLE, acute cutaneous lupus erythematosus; DLE, discoid lupus erythematosus; ANA, antinuclear antibody; SLE, systemic lupus erythematosus.