Table 15.

MolDock molecular docking energies (kJ/mol) for miscellaneous phytochemicals with human estrogen receptors α and β

Compound	Plant Source	ERα	ERβ
10-angeloylbutylphthalide	Angelica sinensis	−96.9	−107.1
ansaspirolide	Angelica sinensis	−98.5	−91.5
asiaticin	Centella asiatica	−96.7	−109.0
3a,7′a:7a,3′a-diligustilide	Angelica sinensis	−94.5	−69.6
3a,8′:6,3′-diligustilide	Angelica sinensis	−91.3	−72.6
3a,8′:6,3′-diligustilidetriepimer	Angelica sinensis	−98.0	−78.1
dioscorealide A	Dioscorea spp.	−92.1	−97.1
dioscorealide B	Dioscorea spp.	−86.2	−98.7
diospongin A	Dioscorea spp.	−95.1	−104.8
diospongin B	Dioscorea spp.	−97.1	−103.9
diospongin C	Dioscorea spp.	−96.1	−107.9
gelispirolide	Angelica sinensis	−64.7	−84.8
homosenkyunolide H	Angelica sinensis	−83.8	−88.7
homosenkyunolide I	Angelica sinensis	−84.3	−92.2
homosilphiperfoloic acid	Centella asiatica	−83.0	−77.3
levistolide A	Angelica sinensis	−86.5	−86.4
neodiligustilide	Angelica sinensis	−78.3	−6.6
orobanchyl acetate	Trifolium pratense	−111.3	−122.8
riligustilide	Angelica sinensis	−71.2	−81.6
senkyunolide O	Angelica sinensis	−84.8	−91.3
sinaspirolide	Angelica sinensis	−86.8	−66.2
3,3a,7a,8-tetrahydro-3,6′:7a,7′-diligustilid-8-one	Angelica sinensis	−80.8	−99.2
estradiol	Positive control	−92.0	−100.0
zearalenone	Positive control	−104.1	−104.9