Table 5. Expressions of Sarcosine Metabolism-Related Proteins in IDC and ILC.
| Parameters | Total, n=835 (%) | Normal tissue, n=30 (%) | IDC, n=721 (%) | ILC, n=114 (%) | p value |
|---|---|---|---|---|---|
| GNMT | 0.231 | ||||
| Negative | 771 (92.3) | 30 (100.0) | 664 (92.1) | 107 (93.9) | |
| Positive | 64 (7.7) | 0 (0.0) | 57 (7.9) | 7 (6.1) | |
| SARDH | 0.045 | ||||
| Negative | 691 (82.8) | 30 (100.0) | 597 (82.8) | 94 (82.5) | |
| Positive | 144 (17.2) | 0 (0.0) | 124 (17.2) | 20 (17.5) | |
| PIPOX | <0.001 | ||||
| Negative | 612 (73.3) | 28 (93.3) | 570 (79.1) | 42 (36.8) | |
| Positive | 223 (26.7) | 2 (6.7) | 151 (20.9) | 72 (63.2) |
IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; GNMT, glycine N-methyltransferase; SARDH, sarcosine dehydrogenase; PIPOX, l-pipecolic acid oxidase.