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. 2015 Apr 1;56(3):658–665. doi: 10.3349/ymj.2015.56.3.658

Table 2. The Protocol for Replacement of Electrolytes and Anticoagulation during CRRT.

Electrolytes
 K+ (mEq/L)
  >4.5 No KCl mix in the 5 L hemozol®
  3.6-4.5 20 mEq KCl mix in the 5 L hemozol®
  <3.6 40 mEq KCl mix in the 5 L hemozol®
 P (mEq/L)
  ≥2.0 No phosten® mix in the 5 L hemozol®
  <2.0 20 mL phosten® mix in the 5 L hemozol®
Anticoagulation
 Initial
  High risk No anticoagulation/saline flushing
  Low risk Systemic heparinization
 Maintenance
  High risk-1 No anticoagulation/saline flushing
  High risk-2 Regional anticoagulation (citrate or nafamostat)
  Low risk Systemic heparinization

CRRT, continuous renal replacement therapy.

Potassium and phosphate level check 2 times per day. Phosten®; potassium phosphate. Hemosol®; hemozol B0. Definitions; 1) High risk; active bleeding, post-operative within 48 hours, low platelet count <50000/mm3, prolonged PT/PTT ≥2.0 INR/60 sec. 2) Low risk; all patients except for high risk patients. 3) High risk-1 and high risk-2 were divided according to assessment of clotting in extracorporeal system during CRRT.