Table 4. Multiple Linear Regression Analysis of the Correlation between Various Confounding Factors and HOMA-IR of Subjects Categorized by Body Mass Index.

Variables	β (p value)
	Total, n=458	Non-obese (<25.0 kg/m2), n=352	Obese (≥25.0 kg/m2), n=106
Age (yrs)	-0.114 (0.125)	-0.215 (0.214)	0.193 (0.642)
BMI (kg/m2)	0.423 (<0.001)*	0.333 (0.638)	1.86 (0.215)
SBP (mm Hg)	0.127 (0.023)*	0.104 (0.050)	-0.021 (0.919)
DBP (mm Hg)	0.127 (0.023)*	0.081 (0.490)	0.001 (0.995)
ALT/AST ratio	0.165 (0.002)*	0.028 (0.610)	0.284 (0.006)*
TC (mg/dL)	-0.165 (0.013)*	-0.283 (0.011)*	-0.314 (0.129)
TG (mg/dL)	0.278 (<0.001)*	0.312 (<0.001)*	0.335 (0.002)*
HDL-C (mg/dL)	-0.253 (<0.001)*	-0.251 (<0.001)*	0.141 (0.496)
LDL-C (mg/dL)	0.310 (0.001)*	0.254 (0.024)*	0.437 (0.040)*
hs-CRP (mg/dL)	0.155 (<0.001)*	0.112 (0.034)*	0.015 (0.868)
R2	0.406 (0.030)*	0.269 (0.050)	0.334 (0.010)*

BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; hs-CRP, high sensitivity C-reactive protein; HOMA-IR, homeostasis model assessment of insulin resistance.

Data for ALT/AST ratio, total cholesterol, triglycerides, LDL-C were skewed and log-transformed for analysis.

^*p value<0.05.