Figure 1.

Flow chart of generating the connectivity matrices for neonate, toddler, and preadolescent groups from DTI and structural MRI. Data from a typical neonate, toddler, and preadolescent brain were used to demonstrate the image analysis process. (a) shows the high-resolution DTI color-encoded map for the subject at each cross-sectional age and corresponding cortical parcellation. With each cortical node as region of interest to initialize DTI tractography, and (b) shows the probabilistic tractography of these subjects. With the information from both cortical parcellation in (a) and probabilistic tracking in (b) for node and weighted edge definition, respectively, the connectivity matrices were built up for these subjects as shown in (c). Preado is the abbreviation of preadolescent.