Figure 3. Resolution of mitochondrial fraction proteins by 2D gel electrophoresis.
Representative gel demonstrating the resolution of 100 μg of human donor RPE mitochondrial fraction protein. Proteins were separated in the first dimension using a nonlinear pH gradient from 3 to 11 and in the second dimension using 13% SDS-polyacrylamide gel electrophoresis, then stained with silver. Spots that changed significantly by one-way ANOVA or linear regression analysis are boxed and numbered according to Table 2.