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. 2015 Apr 15;35(15):5969–5982. doi: 10.1523/JNEUROSCI.4668-14.2015

Figure 4.

Figure 4.

CVN-AD pathology is associated with arginase-1. A, Representative sagittal sections from CVN-AD mice at 6, 12, 24, and 52 weeks of age stained for arginase-1 in sister sections from the same mice as in Figure 1. Scale bar, 500 μm. B, Magnified view of arginase immunoreactivity in the subiculum. Representative sagittal sections from 24-week-old mNos2−/− and CVN-AD stained for arginase-1. Scale bars: top, 500 μm; bottom, 50 μm. C, Sister coronal sections from the same 52-week-old CVN-AD brain stained for Aβ, CD11c, Iba-1, and arginase-1 to show regional associations.